BiologicalActivity
Activeisomerof(±)-trans-ACPD(Cat.No.0187).AgonistatbothgroupIandIImGlureceptors(EC50valuesare5,15,42and60μMatmGluR2,mGluR5,mGluR1andmGluR6respectively).NPEC-caged-(1S,3R)-ACPDalsoavailable(Cat.No.3331).(±)-trans-ACPD(Cat.No.0187)andcis-ACPD(Cat.No.0186)alsoavailable.
TechnicalData
| M.Wt | 173.17 |
| Formula | C7H11NO4 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 111900-32-4 |
| PubChemID | 104766 |
| InChIKey | YFYNOWXBIBKGHB-FBCQKBJTSA-N |
| Smiles | N[C@]1([C@@](O)=O)C[C@]([H])([C@](O)=O)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| 1eq.NaOH | 17.32 | 100 | |
| water | 5.2 | 30 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight173.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.77mL | 28.87mL | 57.75mL |
| 5mM | 1.15mL | 5.77mL | 11.55mL |
| 10mM | 0.58mL | 2.89mL | 5.77mL |
| 50mM | 0.12mL | 0.58mL | 1.15mL |
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