BiologicalActivity
Equimolecularmixtureof(1S,3R)-and(1R,3S)-ACPD.Selectiveagonistformetabotropicglutamatereceptors;activeatbothgroupIandgroupIImGlureceptors(EC50valuesare2,15,23and~800μMatmGluR2,mGluR1,mGluR5andmGluR4respectively).(1S,3R)-ACPD(Cat.No.0284)andcis-ACPD(Cat.No.0186)alsoavailable.
TechnicalData
| M.Wt | 173.17 |
| Formula | C7H11NO4 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 67684-64-4 |
| PubChemID | 23789032 |
| InChIKey | DXLSPTHQGVGVTN-NAAZMWONSA-N |
| Smiles | [H][C@@]1(CC[C@@](N)(C1)C(O)=O)C(O)=O.[H][C@]1(CC[C@](N)(C1)C(O)=O)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| 1eq.NaOH | 8.66 | 50 | |
| water | 5mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight173.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.77mL | 28.87mL | 57.75mL |
| 5mM | 1.15mL | 5.77mL | 11.55mL |
| 10mM | 0.58mL | 2.89mL | 5.77mL |
| 50mM | 0.12mL | 0.58mL | 1.15mL |
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