品牌试剂实验Tocris代理 Tocris Bioscience美元价/进货价,Tocris/ACT 462206/5319/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ACT 462206/5319/50/50 mg

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Tocris

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5319/50

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Description:Potent,dualorexinreceptorantagoNIST

ChemicalName:(2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,dualorexinreceptorantagonist(IC₅₀valuesare11and60nMforOX₂andOX₁receptorsrespectively).Exhibitsanxiolytic-likepropertiesinvivo.Brainpenetrant.

CompoundLibraries

ACT462206isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	388.48
Formula	C₂₀H₂₄N₂O₄S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	1361321-96-1
PubChemID	40924317
InChIKey	NHPQGZOBHSVTAQ-IBGZPJMESA-N
Smiles	CC1=CC(NC([C@@H]2CCCN2S(C3=CC=C(OC)C=C3)(=O)=O)=O)=CC(C)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.85	100
	ethanol	38.85	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.87mL	25.74mL
5mM	0.51mL	2.57mL	5.15mL
10mM	0.26mL	1.29mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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