Tocris厂家直采，平行进口 Tocris离子通道调控剂,Tocris/AH 7614/5256/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/AH 7614/5256/10/10 mg

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Tocris

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5256/10

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4000-520-616

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Description:SelectiveFFA4(GPR120)antagoNIST

ChemicalName:4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivefreefattyacidreceptor4(FFA4/GPR120)antagonist(pIC₅₀valuesare7.1and<4.6forhumanFFA4andFFA1receptorsrespectively).InhibitslinoleicacidandGSK137647A-inducedintracellularcalciumaccumulationinU2OSosteosarcomacellsexpressingtheFFA4receptor.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline

CompoundLibraries

AH7614isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	351.42
Formula	C₂₀H₁₇NO₃S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	6326-06-3
PubChemID	233085
InChIKey	OZCQEUZTOAAWDK-UHFFFAOYSA-N
Smiles	CC(C=C4)=CC=C4S(NC2C3=C(C=CC=C3)OC1=CC=CC=C12)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	35.14	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight351.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.85mL	14.23mL	28.46mL
5mM	0.57mL	2.85mL	5.69mL
10mM	0.28mL	1.42mL	2.85mL
50mM	0.06mL	0.28mL	0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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