Tocris抗体，试剂，血清，细胞 Tocris Bioscience授权代理商，正品,Tocris/AM 251/1117/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/AM 251/1117/10/10 mg

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Tocris

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1117/10

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4000-520-616

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Description:PotentCB₁antagoNIST;alsoGPR55agonist

ChemicalName:N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentCB₁receptorantagonist(IC₅₀=8nM,K_i=7.49nM)thatdisplays306-foldselectivityoverCB₂receptors.AlsopotentGPR55agonist(EC₅₀=39nM).Alsoavailableinafluorescentform(Cat.No.2540).

TechnicalData

M.Wt	555.24
Formula	C₂₂H₂₁Cl₂IN₄O
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	183232-66-8
PubChemID	2125
InChIKey	BUZAJRPLUGXRAB-UHFFFAOYSA-N
Smiles	CC1=C(N(N=C1C(=O)NN1CCCCC1)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(I)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	55.52	100
	ethanol	13.88	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight555.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.8mL	9.01mL	18.01mL
5mM	0.36mL	1.8mL	3.6mL
10mM	0.18mL	0.9mL	1.8mL
50mM	0.04mL	0.18mL	0.36mL

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PreparingStockSolutions

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