商品信息
联系客服
郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Description:PotentandselectiveCXCR4antagoNIST
ChemicalName:N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanaminehexahydrobromide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potent,selectiveCXCR4antagonist;exhibits8-foldhigheraffinitythanAMD3100(Cat.No.3299).InhibitsSDF-1α-ligandbinding(Ki=41.7nM).PotentlyinhibitsHIVcellentryinvitro;causesleukocytosisandmobilizeshaematopoieticstemcellsinvivo.
CompoundLibraries
AMD3465hexahydrobromideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 896.07 |
Formula | C24H38N6.6HBr |
Storage | Storeat-20°C |
Purity | ≥97%(HPLC) |
CASNumber | 185991-07-5 |
PubChemID | 9897616 |
InChIKey | ARHBIBDGWDRBJH-UHFFFAOYSA-N |
Smiles | C1(CN3CCCNCCNCCCNCC3)=CC=C(CNCC2=NC=CC=C2)C=C1.Br.Br.Br.Br.Br.Br |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 22.4 | 25 | |
water | 44.8 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight896.07.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.12mL | 5.58mL | 11.16mL |
5mM | 0.22mL | 1.12mL | 2.23mL |
10mM | 0.11mL | 0.56mL | 1.12mL |
50mM | 0.02mL | 0.11mL | 0.22mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
▍
品牌分类
▍
官网分类
▍
品牌问答