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Tocris/AMI-193/0524/50/50 mg
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Tocris/AMI-193/0524/50/50 mg
品牌 / 
Tocris
货号 / 
0524/50
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4000-520-616
Description:D2-likereceptorantagoNIST
ChemicalName:8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]-decanone
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selective5-HTantagonist,whichbindsto5-HT2sitesaspotentlyasspiperonebuthasloweraffinityfor5-HT2Creceptors.AlsoahighaffinityD2receptorantagonist(Ki=3nM).Lacksthedisruptiveeffectofspiperoneonanimalbehavior.

TechnicalData

M.Wt383.46
FormulaC22H26FN3O2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber510-74-7
PubChemID68186
InChIKeyFJUKDAZEABGEIH-UHFFFAOYSA-N
SmilesFC(C=C4)=CC=C4OCCCN1CCC2(N(C3=CC=CC=C3)CNC2=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.7675
ethanol1.925mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight383.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.61mL13.04mL26.08mL
5mM0.52mL2.61mL5.22mL
10mM0.26mL1.3mL2.61mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet