BiologicalActivity
SelectivegroupIIImetabotropicglutamatereceptoragonist.Synapticdepressant.Agonistatthequisqualate-sensitizedAP6siteinhippocampus.AlsoavailableaspartoftheGroupIIImGluReceptorTocriset™andMixedmGluReceptorTocriset™.DLMixture(Cat.No.0101)andD-isomer(Cat.No.0102)alsoavailable.
TechnicalData
| M.Wt | 183.1 |
| Formula | C4H10NO5P |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 23052-81-5 |
| PubChemID | 179394 |
| InChIKey | DDOQBQRIEWHWBT-VKHMYHEASA-N |
| Smiles | [H][C@@](CCP(O)(O)=O)(N)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| 1eq.NaOH | 18.31 | 100 | |
| water | 0.92 | 5 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight183.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.46mL | 27.31mL | 54.61mL |
| 5mM | 1.09mL | 5.46mL | 10.92mL |
| 10mM | 0.55mL | 2.73mL | 5.46mL |
| 50mM | 0.11mL | 0.55mL | 1.09mL |
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