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Tocris/AR-C 66096 tetrasodium salt/3321/1/1 mg
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Tocris/AR-C 66096 tetrasodium salt/3321/1/1 mg
品牌 / 
Tocris
货号 / 
3321/1
美元价:
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数    量:
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4000-520-616
Description:PotentandselectiveP2Y12antagoNIST
AlternativeNames:FPL66096,ARL66096
ChemicalName:2-(Propylthio)adenosine-5'-O-(β,γ-difluoromethylene)triphosphatetetrasodiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveP2Y12receptorantagonist.BlocksADP-inducedinhibitionofadenylylcyclaseinvitro(pKB=7.6)andinhibitsADP-inducedaggregationofwashedhumanplatelets(pIC50=8.16).

LicensingInformation

SoldforresearchpurposesunderagreementfromAstraZeneca

TechnicalData

M.Wt703.26
FormulaC14H18F2N5Na4O12P3S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber145782-74-7
PubChemID90488830
InChIKeyIETVOLFQZIGNAQ-HVYRMSERSA-J
Smiles[Na+].[Na+].[Na+].[Na+].CCCSC1=NC(N)=C2N=CN([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O)[C@@H](O)[C@H]3O)C2=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinwater(suppliedpre-dissolvedataconcentrationof10mM)

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight703.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.42mL7.11mL14.22mL
5mM0.28mL1.42mL2.84mL
10mM0.14mL0.71mL1.42mL
50mM0.03mL0.14mL0.28mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet