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Tocris/AR-C 69931 tetrasodium salt/5720/1/1 mg
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Tocris/AR-C 69931 tetrasodium salt/5720/1/1 mg
品牌 / 
Tocris
货号 / 
5720/1
美元价:
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数    量:
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4000-520-616
Description:HighlypotentP2Y12antagoNIST
AlternativeNames:Cangrelortetrasodiumsalt
ChemicalName:N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine-5'-O-(β,γ-dichloromethylene)triphosphatetetrasodiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighlypotentP2Y12antagonist(IC50=0.4nM).InhibitsADP-inducedhumanplateletaggregationexvivo.Reducesthrombusweightanddelaysthrombusformationinamodelofcarotidarterythrombosisinvivo.

TechnicalData

M.Wt864.29
FormulaC17H21Cl2F3N5Na4O12P3S2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber163706-36-3
PubChemID10260031
InChIKeyCOWWROCHWNGJHQ-OPKBHZIBSA-J
SmilesO[C@@H]1[C@H](O)[C@@H](N2C3=NC(SCCC(F)(F)F)=NC(NCCSC)=C3N=C2)O[C@H]1COP(OP(C(Cl)(Cl)P(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water86.43100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight864.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.16mL5.79mL11.57mL
5mM0.23mL1.16mL2.31mL
10mM0.12mL0.58mL1.16mL
50mM0.02mL0.12mL0.23mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet