BiologicalActivity
Non-peptidic,low-internalizingδ-selectiveopioidreceptoragonist;derivativeofSNC80(Cat.No.0764).Doesnottriggeracutedesensitizationoftheanalgesicresponse;reducesCFA-inducedhyperalgesia.Brainpenetrantfollowingsystemicadministration.
TechnicalData
| M.Wt | 384.94 |
| Formula | C23H28N2O.HCl |
| Storage | Storeat-20°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 209808-47-9 |
| PubChemID | 76848958 |
| InChIKey | OTXTZCLQEGSAMW-UHFFFAOYSA-N |
| Smiles | O=C(N(CC)CC)C1=CC=C(/C(C3=CC=CC=C3)=C2CCNCC2)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 38.49 | 100 | |
| water | 38.49 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight384.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.6mL | 12.99mL | 25.98mL |
| 5mM | 0.52mL | 2.6mL | 5.2mL |
| 10mM | 0.26mL | 1.3mL | 2.6mL |
| 50mM | 0.05mL | 0.26mL | 0.52mL |
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