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Description:α2BantagoNIST
ChemicalName:2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolindionedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selectiveα2Badrenoceptorantagonist(pKDvaluesare8.8,6.7and6.4atα2B,α2A,andα2Dreceptorsrespectively).Alsoavailableaspartoftheα2-AdrenoceptorTocriset™.
LicensingInformation
SoldwiththepermissionofBoehringerIngelheimGmbH
TechnicalData
| M.Wt | 480.43 |
| Formula | C24H29N3O3.2HCl |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 55974-42-0 |
| PubChemID | 10345075 |
| InChIKey | SAJKHRHHDGSJEZ-UHFFFAOYSA-N |
| Smiles | Cl.Cl.COC1=CC=CC=C1N1CCN(CCN2C(=O)C3=C(C=CC=C3)C(C)(C)C2=O)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 48.04 | 100 | |
| water | 48.04 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight480.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.08mL | 10.41mL | 20.81mL |
| 5mM | 0.42mL | 2.08mL | 4.16mL |
| 10mM | 0.21mL | 1.04mL | 2.08mL |
| 50mM | 0.04mL | 0.21mL | 0.42mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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