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Description:Potent5-HT7agoNIST
ChemicalName:(2S)-(+)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potent5-HT7receptoragonist(IC50=0.83nM).Enhancesmemoryconsolidationandreversesscopolamine-ordizocilpine-inducedamnesiainvivo.
TechnicalData
M.Wt | 283.41 |
Formula | C18H25N3 |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 1000578-26-6 |
PubChemID | 23642275 |
InChIKey | BTTOYOKCLDAHHO-HNNXBMFYSA-N |
Smiles | CC1=C(C2=CC=CC3=C2CC[C@H](N(C)C)C3)C(C)=NN1C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 28.34 | 100 | |
ethanol | 28.34 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight283.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.53mL | 17.64mL | 35.28mL |
5mM | 0.71mL | 3.53mL | 7.06mL |
10mM | 0.35mL | 1.76mL | 3.53mL |
50mM | 0.07mL | 0.35mL | 0.71mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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