Tocris授权代理商，正品 Tocris GPCR ligands,Tocris/ATI 2341/5795/1/1 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ATI 2341/5795/1/1 mg

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Tocris

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5795/1

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4000-520-616

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Description:CXCR4allostericagoNIST

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CXCR4allostericagonist(EC₅₀=194nM).InduceschemotaxisinCXCR4-expressingcellsinvitro.Mobilizespolymorphonuclearneutrophils(PMNs)andhematopoieticstemandProgenitorcells(HSPCs)frombonemarrownicheinvivo.ExhibitsbiasedsignalingtowardsG_iproteinsoverG₁₃andβ-arrestin.

TechnicalData

M.Wt	2256.82
Formula	C₁₀₄H₁₇₈N₂₆O₂₅S₂
Sequence	MGYQKKLRSMTDKYRL (Modifications:Met-1=N-terminalPalmitoyl)
Storage	Storeat-20°C
CASNumber	1337878-62-2
PubChemID	101961246
InChIKey	YMLOFEANRZSEGQ-QNHYGVTPSA-N
Smiles	CCCCCCCCCCCCCCCC(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto1mg/mlinwater

Solubility

Solubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2256.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.44mL	2.22mL	4.43mL
5mM	0.09mL	0.44mL	0.89mL
10mM	0.04mL	0.22mL	0.44mL
50mM	0.01mL	0.04mL	0.09mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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