BiologicalActivity
HighlypotentNMDAantagonist;moreactiveisomer.ShowssomeselectivityforNR2A-containingreceptors(Kivaluesare0.041,0.27,0.63and1.99μMforinhibitionofNR2A-,NR2B-,NR2C-andNR2D-containingrecombinantNMDAreceptorsrespectively).(RS)-CPP(Cat.No.0173)alsoavailable.
TechnicalData
| M.Wt | 252.21 |
| Formula | C8H17N2O5P |
| Storage | DesiccateatRT |
| CASNumber | 126453-07-4 |
| PubChemID | 6603754 |
| InChIKey | CUVGUPIVTLGRGI-SSDOTTSWSA-N |
| Smiles | [H][C@@]1([C@](O)=O)NCCN(CCCP(O)(O)=O)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| phosphatebufferedsaline | 25.22 | 100 | |
| water | 25.22 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight252.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.96mL | 19.82mL | 39.65mL |
| 5mM | 0.79mL | 3.96mL | 7.93mL |
| 10mM | 0.4mL | 1.98mL | 3.96mL |
| 50mM | 0.08mL | 0.4mL | 0.79mL |
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