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Description:Potent,competitiveNMDAantagoNIST
AlternativeNames:Midafotel,SDZEAA494
ChemicalName:D-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylicacid
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentandcompetitiveNMDAantagonist(Ki=40nM).Centrallyactivefollowingsystemicadministration.
TechnicalData
| M.Wt | 250.19 |
| Formula | C8H15N2O5P |
| Storage | DesiccateatRT |
| CASNumber | 117414-74-1 |
| PubChemID | 6435801 |
| InChIKey | VZXMZMJSGLFKQI-ABVWVHJUSA-N |
| Smiles | O=P(/C=C/CN1C[C@H]([C@](O)=O)NCC1)(O)O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 25 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight250.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4mL | 19.98mL | 39.97mL |
| 5mM | 0.8mL | 4mL | 7.99mL |
| 10mM | 0.4mL | 2mL | 4mL |
| 50mM | 0.08mL | 0.4mL | 0.8mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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