BiologicalActivity
AMPAreceptorpotentiator.BindsspecificallytotheagoNISTboundnon-desensitizedreceptor,mostlikelydestABIlizingthedesensitizedreceptorconformation.Enhancescognitivefunctioninrats.Neuroprotectiveinmiceundergoingrepeatketamineanesthesia.
TechnicalData
| M.Wt | 247.29 |
| Formula | C14H17NO3 |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 215923-54-9 |
| PubChemID | 2890 |
| InChIKey | LJUNPHMOGNFFOS-UHFFFAOYSA-N |
| Smiles | O=C(N3CCCCC3)C2=CC1=C(C=C2)OCCO1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.73 | 100 | |
| ethanol | 24.73 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight247.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.04mL | 20.22mL | 40.44mL |
| 5mM | 0.81mL | 4.04mL | 8.09mL |
| 10mM | 0.4mL | 2.02mL | 4.04mL |
| 50mM | 0.08mL | 0.4mL | 0.81mL |
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