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Description:PrototypicvanilloidreceptoragoNIST
ChemicalName:(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Prototypicvanilloidreceptoragonist(pEC50valuesare7.97and7.10atratandhumanVR1receptorsrespectively).Excitesasubsetofprimaryafferentsensoryneurons,withsubsequentantinociceptiveandanti-inflammatoryeffects.ReversIBLyinhibitsaggregationofplatelets.AlsoavailableaspartoftheVanilloidTRPV1ReceptorTocriset™.
TechnicalData
M.Wt | 305.42 |
Formula | C18H27NO3 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 404-86-4 |
PubChemID | 1548943 |
InChIKey | YKPUWZUDDOIDPM-SOFGYWHQSA-N |
Smiles | COC1=C(O)C=CC(CNC(=O)CCCCC=CC(C)C)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 15.27 | 50 | |
ethanol | 15.27 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight305.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.27mL | 16.37mL | 32.74mL |
5mM | 0.65mL | 3.27mL | 6.55mL |
10mM | 0.33mL | 1.64mL | 3.27mL |
50mM | 0.07mL | 0.33mL | 0.65mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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