BiologicalActivity
Inhibitorofneuronalvoltage-gatedNa+channels.Exhibitsanticonvulsantactivity.PotentiatesGABA-inducedCl-currentsinHEK293cellsexpressingtheGABAAreceptorα1β2γ2subtypecombination.Caninduceautophagybyinhibitinginositolsynthesis.
CompoundLibraries
CarbamazepineisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 236.27 |
| Formula | C15H12N2O |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 298-46-4 |
| PubChemID | 2554 |
| InChIKey | FFGPTBGBLSHEPO-UHFFFAOYSA-N |
| Smiles | NC(N1C3=C(C=CC=C3)C=CC2=C1C=CC=C2)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 23.63 | 100 | |
| ethanol | 5.91 | 25 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight236.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.23mL | 21.16mL | 42.32mL |
| 5mM | 0.85mL | 4.23mL | 8.46mL |
| 10mM | 0.42mL | 2.12mL | 4.23mL |
| 50mM | 0.08mL | 0.42mL | 0.85mL |
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