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Description:Gapjunctionblocker.Alsoinhibitorof11β-hydroxysteroiddehydrogenase
ChemicalName:(3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oicaciddisodium
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Glucocorticoidthatinhibits11β-hydroxysteroiddehydrogenase(11-HSD)andblocksgapjunctioncommunication.
TechnicalData
| M.Wt | 614.72 |
| Formula | C34H48Na2O7 |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 7421-40-1 |
| PubChemID | 636402 |
| InChIKey | BQENDLAVTKRQMS-SBBGFIFASA-L |
| Smiles | [Na+].[Na+].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CCC([O-])=O)C(C)(C)[C@]3([H])CC[C@@]12C)C([O-])=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 61.47 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight614.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.63mL | 8.13mL | 16.27mL |
| 5mM | 0.33mL | 1.63mL | 3.25mL |
| 10mM | 0.16mL | 0.81mL | 1.63mL |
| 50mM | 0.03mL | 0.16mL | 0.33mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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