Tocris授权代理商，正品 Tocris化合物筛选文库,Tocris/DMH4/4471/50/50 mg,激酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/DMH4/4471/50/50 mg

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Tocris

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4471/50

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4000-520-616

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Description:SelectiveVEGFR-2inhibitor

ChemicalName:6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-3-phenylpyrazolo[1,5-a]pyrimidine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveVEGFR-2inhibitor(IC₅₀valuesare161,3558,8038and>30000nMforVEGFR-2,BMPR-I,AMPKandTGFβR-Irespectively).Displaysantiangiogenicactivityinvitroandinvivo.

CompoundLibraries

DMH4isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	400.47
Formula	C₂₄H₂₄N₄O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	515880-75-8
PubChemID	5329447
InChIKey	SKZQZGSPYYHTQG-UHFFFAOYSA-N
Smiles	C(C=N2)(C4=CC=C(OCCN5CCOCC5)C=C4)=CN1C2=C(C3=CC=CC=C3)C=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	20.02	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight400.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.5mL	12.49mL	24.97mL
5mM	0.5mL	2.5mL	4.99mL
10mM	0.25mL	1.25mL	2.5mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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PreparingStockSolutions

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