Tocris型号参数规格 Tocris离子通道调控剂,Tocris/DMPQ dihydrochloride/1222/10/10 mg,激酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/DMPQ dihydrochloride/1222/10/10 mg

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Tocris/DMPQ dihydrochloride/1222/10/10 mg

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Tocris

货号 /

1222/10

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4000-520-616

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Description:Potent,selectiveinhibitorofPDGFRβ

ChemicalName:5,7-Dimethoxy-3-(4-pyridinyl)quinolinedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Apotentandselectiveinhibitorofhumanvascularβ-typeplateletderivedgrowthfactorreceptortyrosinekinase(PDGFRβ)(IC₅₀=80nM).Displays>100-foldselectivityoverEGFRtyrosinekinase,erbB2,p56,proteinkinaseAandproteinkinaseC.

TechnicalData

M.Wt	339.22
Formula	C₁₆H₁₄N₂O₂.2HCl
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	1123491-15-5
PubChemID	45073427
InChIKey	YBBAOKYVJCNJIV-UHFFFAOYSA-N
Smiles	COC1=CC(OC)=C2C(N=CC(C3=CC=NC=C3)=C2)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinwater

Solubility

Solubleto100mMinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight339.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.95mL	14.74mL	29.48mL
5mM	0.59mL	2.95mL	5.9mL
10mM	0.29mL	1.47mL	2.95mL
50mM	0.06mL	0.29mL	0.59mL

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SolubilityData

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