Tocris试剂采购 Tocris Bioscience代理，产品目录,Tocris/GW 441756/2238/10/10 mg,激酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/GW 441756/2238/10/10 mg

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Tocris

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2238/10

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Description:Potent,selectiveTrkAinhibitor

ChemicalName:1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveinhibitoroftheNGFreceptortyrosinekinaseA(TrkA)(IC₅₀=2nM).Displays>100-foldselectivityoverarangeofotherkinases.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline.

TechnicalData

M.Wt	275.31
Formula	C₁₇H₁₃N₃O
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	504433-23-2
PubChemID	16219401
InChIKey	NXNQLECPAXXYTR-UHFFFAOYSA-N
Smiles	CN1C=C(C=C2C(=O)NC3=CC=CN=C23)C2=C1C=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.13	15

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight275.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.63mL	18.16mL	36.32mL
5mM	0.73mL	3.63mL	7.26mL
10mM	0.36mL	1.82mL	3.63mL
50mM	0.07mL	0.36mL	0.73mL

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CertificateofAnalysis/ProductDatasheet

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SolubilityData

PreparingStockSolutions

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