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Description:EGFRkinaseinhibitor.AlsoestrogenandPPARγligand
ChemicalName:5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Phytoestrogenwithawiderangeofbiologicalactions.Inhibitsproteintyrosinekinasesincludingepidermalgrowthfactorreceptorkinase.AlsobindstoPPARγandestrogenreceptorsandactsasanagoNISTatGPER.AlsoavailableaspartoftheMAPKCascadeInhibitorTocriset™.
CompoundLibraries
GenisteinisalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 270.24 |
Formula | C15H10O5 |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 446-72-0 |
PubChemID | 2252 |
InChIKey | PIXJURSCCVBKRF-UHFFFAOYSA-N |
Smiles | OC1=CC=C(C=C1)C1=COC2=C(C(O)=CC(O)=C2)C1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto100mMinDMSO |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight270.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.7mL | 18.5mL | 37mL |
5mM | 0.74mL | 3.7mL | 7.4mL |
10mM | 0.37mL | 1.85mL | 3.7mL |
50mM | 0.07mL | 0.37mL | 0.74mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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