Tocris公司代理生物计划 Tocris Bioscience产品促销,Tocris/Lavendustin A/1331/1/1 mg,激酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Lavendustin A/1331/1/1 mg

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Tocris

货号 /

1331/1

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4000-520-616

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Description:EGFR,p60^c-srcinhibitor

AlternativeNames:RG14355

ChemicalName:5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,cell-permeableinhibitorofepidermalgrowthfactorreceptor(EGFR)tyrosinekinase(IC₅₀=11nM).Inhibitsp60^c-srcwithanIC₅₀of500nMandisselectiveoverPKA,PKCandPI3-kinase(IC₅₀>100μM).

TechnicalData

M.Wt	381.38
Formula	C₂₁H₁₉NO₆
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	125697-92-9
PubChemID	11317883
InChIKey	JJSYXNQGLHBRRK-SFEDZAPPSA-N
Smiles	OC1=CC=C(O)C=C1CN(CC3=C(O)C=CC=C3)C2=CC=C(O)C(C(O)=O)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.53	25
	ethanol	9.53	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight381.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.62mL	13.11mL	26.22mL
5mM	0.52mL	2.62mL	5.24mL
10mM	0.26mL	1.31mL	2.62mL
50mM	0.05mL	0.26mL	0.52mL

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