BiologicalActivity
Highaffinityinsulin-likegrowthfactor-1bindingprotein(IGFBP)inhibitor(Kivaluesare1-24nMforallsixhumansubtypes).Displacesinsulin-likegrowthfactor-1(IGF-1)fromtheIGF-1:IGFBPcomplexandsuppressesIGF1-inducedproliferationof3T3fibroblasts.Alsoincreasescardiomyocyteproliferationinvivo.
TechnicalData
| M.Wt | 341.27 |
| Formula | C17H11NO7 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 374620-70-9 |
| PubChemID | 54684689 |
| InChIKey | QUIWTBSOEFPLHE-FOCLMDBBSA-N |
| Smiles | O=C(C3=CC=C(O)C(O)=C3)C2=NC(C(O)=O)=CC1=CC(O)=C(O)C=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.13 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight341.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.93mL | 14.65mL | 29.3mL |
| 5mM | 0.59mL | 2.93mL | 5.86mL |
| 10mM | 0.29mL | 1.47mL | 2.93mL |
| 50mM | 0.06mL | 0.29mL | 0.59mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。