BiologicalActivity
Peptidefragmentcorrespondingtoresidues368-381ofthehumanp75neurotrophinreceptor(p75NTR).Formsahelicalstructureinthepresenceofmicellarlipid.Inducesapoptosisinhumanneuroblastomacellsinvitro.
TechnicalData
| M.Wt | 1565.87 |
| Formula | C69H124N22O19 |
| Sequence | ATLDALLAALRRIQ-amide (Modifications:Ala-1=N-terminalAc,Gln-14=C-terminalamide) |
| Storage | Desiccateat-20°C |
| CASNumber | 197230-90-3 |
| PubChemID | 90488737 |
| InChIKey | ZUALDXYFESKMAR-SMVIZIMZSA-N |
| Smiles | CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1565.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.64mL | 3.19mL | 6.39mL |
| 5mM | 0.13mL | 0.64mL | 1.28mL |
| 10mM | 0.06mL | 0.32mL | 0.64mL |
| 50mM | 0.01mL | 0.06mL | 0.13mL |
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