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Tocris/SU 5416/3037/10/10 mg
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Tocris/SU 5416/3037/10/10 mg
品牌 / 
Tocris
货号 / 
3037/10
美元价:
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数    量:
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4000-520-616
Description:VEGFRinhibitor.AlsoinhibitsKIT,RET,METandFLT3
AlternativeNames:Semaxinib
ChemicalName:3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofvascularendothelialgrowthfactorreceptor(VEGFR)thatalsoinhibitsothertyrosinekinasesKIT,MET,FLT3andRET.DisplaysnoactivityagainstEGFR,HER2,IGF1RandPDGFR.Inhibitstumorvascularizationandgrowthofmultipletumortypes.

CompoundLibraries

SU5416isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt238.28
FormulaC15H14N2O
StorageDesiccateat-20°C
Purity≥99%(HPLC)
CASNumber204005-46-9
PubChemID5329098
InChIKeyWUWDLXZGHZSWQZ-WQLSENKSSA-N
SmilesO=C2NC1=CC=CC=C1/C2=C/C3=C(C)C=C(C)N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.83100
ethanol2.3810mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight238.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.2mL20.98mL41.97mL
5mM0.84mL4.2mL8.39mL
10mM0.42mL2.1mL4.2mL
50mM0.08mL0.42mL0.84mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet