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Description:Basicfibroblastgrowthfactor(bFGF)mimetic;neuroprotective
ChemicalName:4-[[4-[[2-[(4-Amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]benzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Basicfibroblastgrowthfactor(bFGF)mimetic.MimicstheneuroprotectiveeffectsofbFGF;preventsglutamate-inducedneuronaldeath.IncreaseslevelsofCALB1geneexpressionincerebrocorticalneurons.TriggersphosphorylationofFGFR,ERK1andERK2.
CompoundLibraries
SUN11602isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 451.61 |
| Formula | C26H37N5O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 704869-38-5 |
| PubChemID | 22245705 |
| InChIKey | KCODNOOPOPTZMO-UHFFFAOYSA-N |
| Smiles | NC1=C(C)C(C)=C(NCC(N(C)C2CCN(CC3=CC=C(C(N)=O)C=C3)CC2)=O)C(C)=C1C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.58 | 50 | |
| ethanol | 9.03 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight451.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.21mL | 11.07mL | 22.14mL |
| 5mM | 0.44mL | 2.21mL | 4.43mL |
| 10mM | 0.22mL | 1.11mL | 2.21mL |
| 50mM | 0.04mL | 0.22mL | 0.44mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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