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Tocris/SUN 11602/4826/10/10 mg
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Tocris/SUN 11602/4826/10/10 mg
品牌 / 
Tocris
货号 / 
4826/10
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4000-520-616
Description:Basicfibroblastgrowthfactor(bFGF)mimetic;neuroprotective
ChemicalName:4-[[4-[[2-[(4-Amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]benzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Basicfibroblastgrowthfactor(bFGF)mimetic.MimicstheneuroprotectiveeffectsofbFGF;preventsglutamate-inducedneuronaldeath.IncreaseslevelsofCALB1geneexpressionincerebrocorticalneurons.TriggersphosphorylationofFGFR,ERK1andERK2.

CompoundLibraries

SUN11602isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt451.61
FormulaC26H37N5O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber704869-38-5
PubChemID22245705
InChIKeyKCODNOOPOPTZMO-UHFFFAOYSA-N
SmilesNC1=C(C)C(C)=C(NCC(N(C)C2CCN(CC3=CC=C(C(N)=O)C=C3)CC2)=O)C(C)=C1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.5850
ethanol9.0320

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight451.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.21mL11.07mL22.14mL
5mM0.44mL2.21mL4.43mL
10mM0.22mL1.11mL2.21mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet