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Tocris/AG 556/0616/50/50 mg
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Tocris/AG 556/0616/50/50 mg
品牌 / 
Tocris
货号 / 
0616/50
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数    量:
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4000-520-616
Description:EGFR-kinaseinhibitor
AlternativeNames:TyrphostinAG556
ChemicalName:(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)-2-propenamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Epidermalgrowthfactorreceptor(EGFR)kinaseinhibitor(IC50=1.1μM).SelectiveoverErbB2(IC50>500μM).

TechnicalData

M.Wt336.39
FormulaC20H20N2O3
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber133550-41-1
PubChemID5328775
InChIKeyGWCNJMUSWLTSCW-SFQUDFHCSA-N
SmilesOC1=C(O)C=C(C=C(/C#N)C(=O)NCCCCC2=CC=CC=C2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.0930

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight336.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.97mL14.86mL29.73mL
5mM0.59mL2.97mL5.95mL
10mM0.3mL1.49mL2.97mL
50mM0.06mL0.3mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet