生命科学Tocris价格优惠 Tocris Bioscience美元价/进货价,Tocris/AG 825/1555/10/10 mg,激酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/AG 825/1555/10/10 mg

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Tocris

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1555/10

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4000-520-616

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Description:SelectiveErbB2inhibitor

AlternativeNames:TyrphostinAG825

ChemicalName:(E)-3-[3-[2-Benzothiazolythio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveErbB2inhibitor(IC₅₀valuesare0.15and19μMatErbB2andErbB1respectively).Preferentiallytriggersp38MAPkinase-dependentapoptosisinandrogen-independentprostatecancercells.

TechnicalData

M.Wt	397.47
Formula	C₁₉H₁₅N₃O₃S₂
Storage	Storeat+4°C
CASNumber	149092-50-2
PubChemID	6091659
InChIKey	KXDONFLNGBQLTN-WUXMJOGZSA-N
Smiles	COC1=CC(C=C(/C#N)C(N)=O)=CC(CSC2=NC3=C(S2)C=CC=C3)=C1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	39.75	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight397.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.52mL	12.58mL	25.16mL
5mM	0.5mL	2.52mL	5.03mL
10mM	0.25mL	1.26mL	2.52mL
50mM	0.05mL	0.25mL	0.5mL

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CertificateofAnalysis/ProductDatasheet

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