商品信息
联系客服

郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Description:TrkBreceptorantagoNIST
ChemicalName:N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
TrkBreceptorantagonist.Demonstratesa2-sitemodeofaction,preventingactivationbyBDNFnon-competitively(IC50valuesare45.6nMand41.1μMforthehighandlowaffinitysitesrespectively).DisplaysnoeffectonTrkAandTrkCinanassayofneuriteoutgrowth.Demonstratesantidepressantproperties.
CompoundLibraries
ANA12isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 407.49 |
Formula | C22H21N3O3S |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 219766-25-3 |
PubChemID | 2799722 |
InChIKey | TUSCYCAIGRVBMD-UHFFFAOYSA-N |
Smiles | O=C(NC4C(NCCCC4)=O)C1=C(NC(C2=CC3=C(C=CC=C3)S2)=O)C=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 20.37 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight407.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.45mL | 12.27mL | 24.54mL |
5mM | 0.49mL | 2.45mL | 4.91mL |
10mM | 0.25mL | 1.23mL | 2.45mL |
50mM | 0.05mL | 0.25mL | 0.49mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


▍
品牌分类
▍
官网分类
▍
品牌问答