Description
The carcinoembryonic antigen (CEA) family is composed of 29 genes tandemly arranged on chromosome 19q13.2. Based on nucleotide homologies, these genes are classified into 2 major subfamilies, the CEACAM and the pregnancy-specific glycoprotein (PSG) subgroups. The CEACAM-encoded proteins include CEA, CEACAM1, and other CEA gene members . CEACAM1 (Carcinoembryonic antigen related cell adhesion molecule 1; also BGP1, CD66a), is involved in the regulation of important biological processes, such asinsulin homeostasis , angiogenesis, and modulation of the immune response.
