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BD Biosciences/CD15 FITC/CD117 PE/333177
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BD Biosciences/CD15 FITC/CD117 PE/333177
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Bacteria
货号 / 
333177
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Product DetailsRecommended AssayReferences

Description

BD Oncomark™ CD15 FITC/CD117 PE is intended for in vitro flow cytometric immunophenotyping. CD15/CD117 assays are used in the diagnosis of hematologic disorders.

Contents

SpecificityCloneFormatIsotypeEntrez Gene ID
CD15MMAFITCIgM, κ2526
CD117 (c-Kit)104D2PEIgG13815
Preparation and Storage

The antibody reagent is stable until the expiration date shown on the label when stored at 2° to 8°C. Do not use after the expiration date. Do not freeze the reagent or expose it to direct light during storage or incubation with cells. Keep the outside of the reagent vial dry.

Do not use the reagent if you observe any change in appearance. Precipitation or discoloration indicates instability or deterioration.

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  9. Gunji Y, Nakamura M, Osawa H, et al. Human primitive hematopoietic progenitor cells are more enriched in KITlow cells than in KIThigh cells. Blood. 1993;82:3283-3289.

  10. Hanjan SN, Kearney JF, Cooper MD. A monoclonal antibody (MMA) that identi es a differentiation antigen on human myelomonocytic cells. Clin Immunol Immunopathol. 1982;23:172-188.

  11. Jackson AL, Warner NL. Preparation, staining, and analysis by flow cytometry of peripheral blood leukocytes. In: Rose NR, Friedman H, Fahey JL, eds. Manual of Clinical Laboratory Immunology. 3rd ed. Washington, DC: American Society for Microbiology; 1986:226-235.

  12. Macedo A, Orfao A, Gonzalez M, et al. Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: implications for minimal residual disease studies. Leukemia. 1995;9:993-998.

  13. Matsuo Y, Adachi T, Tsubota T, Imanishi J, Minowada J. Establishment and characterization of a novel megakaryoblastoid cell line, MOLM-1, from a patient with chronic myelogenous leukemia. Human Cell. 1991;4:261-264.

  14. Olweus J, Terstappen LWMM, Thompson PA, Lund-Johansen F. Expression and function of receptors for stem cell factor and erythropoietin during lineage commitment of human hematopoietic progenitor cells. Blood. 1996;88:1594-1607.

  15. Rothe G, Schmitz G. Consensus protocol for the flow cytometric immunophenotyping of hematopoietic malignancies. Leukemia. 1996;10:877-895.

  16. Schwartz S, Heinecke A, Zimmermann M, et al. Expression of the C-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic signicance. Leuk Lymphoma. 1999;34(1-2):85-94.

  17. Simmons P, Aylett G, Niutta S, To L, Juttner C, Ashman L. c-kit is expressed by primitive human hematopoietic cells that give rise to colony-forming cells in stroma-dependent or cytokine-supplemented culture. Exp Hematol. 1994;22:157-165.

  18. Skubitz K, Balke J, Ball E, et al. Report on the CD15 cluster workshop. In: Knapp W, Dörken B, Gilks W, et al, eds. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press Inc; 1989:800-805.

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