Overview

Infect more cells with TransDux™

Increase your transduction efficiencies with TransDux (Original) Virus Transduction Reagent. Simply mix with virus to see 2-fold or greater (depending on cell type) transduction efficiencies over polybrene addition.

Or try our newer TransDux MAX™ Virus Transduction Reagent for an even greater increase in infectivity.

• High transduction efficiency
• Broad cell type compatibility
• Minimal hands-on time

How It Works

Get higher transduction efficiencies with minimal hands-on time

Simply combine culture medium with TransDux to a final concentration of 1x, add to cells, and then add virus. Swirl to mix, and proceed with the transduction as usual—72-hours post transduction, the viral genome will be integrated into the host cell genome.

Supporting Data

Increase transduction efficiencies with TransDux

Figure 1. Our original TransDux Reagent increases transduction efficiencies at least 2-fold compared to polybrene. Transduction of either HepG2 cells (top panels) or HT1080 cells (bottom panels) with the addition of polybrene (left two panels) or TransDux (middle two panels). The right two panels show quantitative measures of infectivity using the Global UltraRapid Titer Kit. Both imaging and infectivity data show that TransDux increased the infectivity of lentivirus in both cell types as compared to polybrene.

Resources

Citations

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