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GenWay/Aldehyde Dehydrogenase Activity Colorimetric Assay Kit /GWB-AXR339/100 assays
免费咨询热线
4000-520-616
Description:
| Description | TheNAD-dependentAldehydeDehydrogenase(ALDH)playsavitalroleincellulardetoxification.Itoxidizesvariousaldehydesandgeneratesthecorrespondingcarboxyolicacid.ALDHhavebeenfoundineverycellularcompartment.Basedonitsstructureandfunction,ALDHcomprises3majorclassesinmammals:Class1andClass3(thetumorform)arelocatedinthecytosolandincludebothconstitutiveandinducedforms;Class2islocatedinthemitochondriaandonlyexistsastheconstitutiveform.Inhumans,theALDHsuperfamilyconsistsof19genes.ThemutationofALDHgenes(lossoffunction)causeshumandiseasessuchasTypeIIhyperprolinemia,pyridoxine-dependentseizureandhyperammonemia.RecentstudiesshowthatincreasedALDHactivityleadstoseveraltypesofmalignancies,servesasacancerstemcellMarkerandcorrelateswithpoorprognosis.ThereforetheearlydetectionofALDHactivitylevelscanbeprognosticandguidethetherapeuticstrategies.TheGenWayAldehydeDehydrogenase(ALDH)ActivityAssayKitisasimple,fastandreliablemethodtoquantifytheALDHenzymaticactivity.Inthisassay,acetaldehydeisoxidizedbyALDHgeneratingNADHwhichthenreducesacolorlessprobetoacoloredproductwithstrongabsorbanceat450nm.Theassaycandetect<0.5mUofALDHactivity(basedonourunitdefinition)inavarietyofsamples. |
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| Summary |
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| Kitcomponents |
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| FeaturesandBenefits | -Simpleprocedure -Fastandconvenient -SensitiveassayformeasuringALDHactivityinvariousbiologicalsamplesandthekitisalsosuitableforhighthroughputanalyses. |
| ShippingConditions | Gelpack |
AdditionalInformation:
| Name | AldehydeDehydrogenaseActivityColorimetricAssayKit |
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| RelatedProductNames | Aldehydedehydrogenaseassay,Aldehydedehydrogenasedetection,Aldehydedehydrogenaseanalysis,Aldehydedehydrogenaseassaykit,MeasureAldehydedehydrogenase,AldehydeDehydrogenaseActivityColorimetricAssayKit,ALDHassaykit,AssayALDH,ALDHdet |
| Format | AssayKit |
| Storage | -20°C |
| IntendedUse | ResearchUseOnly |

