Liposome formulations can be broadly divided into cationic, anionic and neutral subtypes. Charged liposomes are used in many different types of studies such as, blood complement studies, gene transfer studies and other biomedical applications to name a few. Cellsome® liposomes made from cationic PEGylated lipids provide certain benefits. Cationic liposomes interact with negatively charged glycoproteins (i.e. mucins) on the cell surface, thereby increasing the affinity and residence time with the target cells, resulting in increased drug delivery. Conventional liposomal formulations reduced the toxicity of compounds in vivo, through modifying pharmacokinetics and biodistribution to enhance drug delivery to diseased tissue in comparison to free drug. However, the delivery system was prone to rapid elimination from the bloodstream, therefore limiting its therapeutic efficacy. To improve liposome stability and enhance their circulation times in the blood, a sterically stabilized, hydrophilic polymer, polyethylene glycol (PEG), has been shown to be the optimal choice for obtaining sterically stabilized liposomes. Using a Cationic Liposome with PEG will protect the liposomes from circulating proteins, improving their plasma clearance and enhancing their therapeutic effects.
The two products provided that are made from Cationic PEGylated Lipids provided here consist of either DSPC:Chol:DSTAP:DSPE-PEG(2000) (60:30:5:5 molar ratio) or DOPC:Chol:DOTAP:DOPE-PEG(2000) (60:30:5:5 molar ratio).
Lyophosome™ product catalog is composed of a large selection of freeze-dried liposomes with various types of lipids and wide range of zeta potentials and different properties. Lyophosome™ products should be used by scientists who understand liposome formulation and have the proper equipment to check the size, separate non-encapsulated drugs and do the proper assays. Freeze-dried liposomes cannot be used blindly.
ebiomall.com
>
>
>
>
>
>
>
>
>
>
>
DAS-ELISA试剂盒中抗体有包被抗体和酶标抗体,这两种抗体是一种抗体,前者没有酶标,后者用酶进行了标记。
NCM-ELISA一般有一抗和二抗,这两种抗体不一样,前者(一抗)一般是鼠抗体或兔抗体,没有酶标,相对应的二抗一般是羊抗鼠或羊抗兔抗体,用酶进行标记。也有用马大规模备抗体的。
TDS-ELISA是三抗体ELISA,第三级的抗体是将信号级联放大。
以上三种是比较常见的,还有其他一些试剂盒,可参考免疫学的内容。
首先要什么有什么的,你得好好考虑一下。
2、看生产地址
根本没有生产地址,我们知道做实验做产品需要很多的仪器、试剂、耗材,没有人相信一间简单的屋子可以生产各种样的试剂盒。
3、看产品包装
没有任何的生产地址、联系方式等信息,这种产品有问题了连个投诉的地方都没有。
4、看公司网站
有些打着国外原装旗号,整个公司网站为英文页面,实际注册IP地址在中国。如果写着国外的地址,让你国外的朋友实地去看一下!
5、做交叉验证
拿对方提供的几个种类的试剂盒,把里面的关键组份相互替换做做实验,如果交叉严重,只能说明是一种原料生产的试剂盒贴了不同的标签。
6、看价格
价格低得离谱,却打着进口大公司原料分装,核算成本,这种低得离谱的价格是连原料都买不起的。

