
Overview:
DOK1 contains pleckstrin homology domain and ten PXXP SH3 recognition motifs and is a critical substrate for p210 bcr/abl. DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors cells isolated from CML patients (1). DOK1 is associated with p120 Ras-GAP and this association is correlated with its tyrosine phosphorylation. Aberrant phosphorylation of DOK1 may contribute to the progression of different human diseases (2).
References:
1. Carpino, N. et.al: p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 88: 197-204, 1997.2. Yasuda. et.al: Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia. J. Exp. Med. 200: 1681-1687, 2004.
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而国内的只有兔抗牛。
就二抗来说,国内的标记二抗质量也很不错。可以用。
有没有知道哪个公司可以买到几种牛病毒的荧光标记的抗体?
我要做细胞的免疫荧光实验。
1.Bluetongue蓝舌病毒
2.BovineAdenovirus牛腺病毒
3.BovineParvovirus牛细小病毒
4.BovineRespiratorySyncytialVirus牛呼吸道融合病毒
5.BovineVirusDiarrhoea牛腹泻病毒
6.Reovirus呼肠孤病毒-3
7.InfectiousBovineRhinotracheitis,IBR传染性牛鼻气管炎病毒
8.BovineParainfluenzaVirusType3,PI3牛副流行性感冒3型病毒
9.RABIes狂犬病毒
能提供一种的也可以,多谢啊~~~~~~~

