
Overview:
RIPK1 or Receptor Interacting Protein Kinase 1 is a serine/threonine kinase that was originally identified as interacting with the cytoplasmic domain of FAS. RIPK1 has been deemed as an important element in the signal transduction machinery that mediates programmed cell death. RIPK1 has been shown to interact with TRADD, TRAF1 TRAF2 and TRAF3 and TRADD can act as an adaptor protein to recruit RIPK1 to the TNFR1 complex in a TNF-dependent process (1). TNFα is capable of activating the noncanonical NF-κB pathway, but this activation of this pathway is negatively regulated by RIPK1 (2).
References:
1. Hsu, H. et al: TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4: 387-396, 1996. 2. Kim, J Y. et al: TNFα induced noncanonical NF-κB activation is attenuated by RIP1 through stabilization of TRAF2. J Cell Sci. 2011 Feb 15;124(Pt 4):647-56.
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而国内的只有兔抗牛。
就二抗来说,国内的标记二抗质量也很不错。可以用。
有没有知道哪个公司可以买到几种牛病毒的荧光标记的抗体?
我要做细胞的免疫荧光实验。
1.Bluetongue蓝舌病毒
2.BovineAdenovirus牛腺病毒
3.BovineParvovirus牛细小病毒
4.BovineRespiratorySyncytialVirus牛呼吸道融合病毒
5.BovineVirusDiarrhoea牛腹泻病毒
6.Reovirus呼肠孤病毒-3
7.InfectiousBovineRhinotracheitis,IBR传染性牛鼻气管炎病毒
8.BovineParainfluenzaVirusType3,PI3牛副流行性感冒3型病毒
9.RABIes狂犬病毒
能提供一种的也可以,多谢啊~~~~~~~

