

This product is freeze dried. All water molecules have been removed.

This antibody is shipped with its antigen FREE of charge!
- Peptide CKQGFLSSNGQNHFK, corresponding to amino acid residues 58-72 of human EMR1 (Accession Q14246). Extracellular, N-terminus.
- Western blot analysis of rat fat (lanes 1 and 6), mouse fat (lanes 2 and 7), human Burkitt's lymphoma (Raji) (lanes 3 and 8), rat basophilic leukemia (RBL) (lanes 4 and 9) and human promyelocytic leukemia (HL-60) (lanes 5 and 10) lysates:1-5. Anti-EMR1 (ADGRE1) (extracellular) Antibody (#AER-051), (1:400).
6-10. Anti-EMR1 (ADGRE1) (extracellular) Antibody, preincubated with the negative control antigen.
- Expression of EMR1 in rat RBL cellsCell surface detection of EMR1 in intact living rat basophilic leukemia (RBL) cells. A. Extracellular staining of cells using Anti-EMR1 (ADGRE1) (extracellular) Antibody (#AER-051), followed by goat anti-rabbit-AlexaFluor-594 secondary antibody (red), (1:100). B. Live view of the cells. C. Merged image of panels A and B.
- 1. Legrand, F. et al. (2014) J. Allergy Clin. Immunol. 133, 1439.
- 2. McKnight, A.J. and Gordon, S. (1998) J. Leukoc. Biol. 63, 271.
- 3. Araç, D. et al. (2012) EMBO J. 31, 1364.
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Human epidermal growth factor (EGF)–like module containing mucin-like hormone receptor 1 (EMR1) is a surface receptor with unknown function that belongs to the adhesion family of the G protein-coupled receptors (GPCR). This receptor is encoded by the ADGRE1 and like all GPCRs, contains seven transmembrane domains, an intracellular C-terminus and an extracellular N-terminus. The NH2 domain has six EGF-like domains.
Adhesion GPCRs share a long N-terminal extracellular sequences comprising multiple domains, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties1,2.
EMR1 protein is a homolog of F4/80, a murine protein that is widely being used as a marker of murine macrophage populations1.
Human EMR1 is exclusively expressed on mature eosinophils in the blood and bone marrow and in nasal polyps. Thus, EMR1 is considered to be a potential therapeutic target for the treatment of eosinophilic disorders1,3.
Anti-EMR1 (ADGRE1) (extracellular) Antibody (#AER-051) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot and live cell imaging applications. It recognizes an extracellular epitope and is thus ideal for detecting the receptor in living cells. It has been designed to recognize EMR1 from human, mouse, and rat samples.
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而国内的只有兔抗牛。
就二抗来说,国内的标记二抗质量也很不错。可以用。
有没有知道哪个公司可以买到几种牛病毒的荧光标记的抗体?
我要做细胞的免疫荧光实验。
1.Bluetongue蓝舌病毒
2.BovineAdenovirus牛腺病毒
3.BovineParvovirus牛细小病毒
4.BovineRespiratorySyncytialVirus牛呼吸道融合病毒
5.BovineVirusDiarrhoea牛腹泻病毒
6.Reovirus呼肠孤病毒-3
7.InfectiousBovineRhinotracheitis,IBR传染性牛鼻气管炎病毒
8.BovineParainfluenzaVirusType3,PI3牛副流行性感冒3型病毒
9.RABIes狂犬病毒
能提供一种的也可以,多谢啊~~~~~~~

