Epigentek/ALKBH3 Polyclonal Antibody/A57365-050/50 µg
| Application: | ELISA, IF, IHC |
| Areas of Research: | DNA Methylation |
| Clonality: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | >95%, Protein G Purified |
| Reactivity: | Human |
| 100% Guarantee: | 6 months |
BackgroundDioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
DescriptionALKBH3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ96Q83
Purification>95%, Protein G purified
ImmunogenRecombinant human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 protein (1-170AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesAlkylated DNA repair protein alkB homolog 3, DEPC-1, Prostate cancer antigen 1, ABH3, DEPC1, ALKBH3
ApplicationELISA, IHC, IF; Recommended dilution: IHC: 1:20-1:200, IF: 1:50-1:200
VCU0006
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