GenWay/MMP-3 Inhibitor Screening Kit /GWB-AXR369/100 assays
Description:
Description: The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In GenWays MMP-3 Inhibitor Screening Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Em/Ex=325/393 nm. The kit provides a rapid, simple, sensitive, and reliable test suitable as a high throughput screening assay of MMP-3 inhibition.Summary: - Detection method- Fluorescence (Ex/Em 325/393 nm) - Sample type- Test inhibitors for MMP-3 - Applications- The kit can be used to screen inhibitors of MMP-3. Kit components: - MMP-3 Assay Buffer - MMP-3 Substrate - MMP-3 Enzyme (lyophilized) - Inhibitor Control (0.1 mM GM6001) Features and Benefits: - Simple procedure; takes ~ 35-45 minutes - Fast and convenient - The assay is simple, reliable and ensures accuracy and consistency when working with multiple samples. Shipping Conditions: Gel pack
Additional Information:
| MMP-3 Inhibitor Screening Kit |
| MMP-3 assay kit, MMP, MMP-3, Detect MMP-3, MMP3 assay, MMP3 quantification, MMP-3 detection, MMP-3 assay, MMP-3 quantification, MMP3 detection, MMP-3 inhibitor, Screen for MMP-3 inhibitors, MMP-3 inhibitor screening, MMP3 inhibitor, Screen for MMP3 inhibi |
| Assay Kit |
| -20C |
| Research Use Only |
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