GenWay/MMP-3 Activity Assay Kit /GWB-AXR358/100 assays
Description:
Description: The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In GenWay’s MMP-3 Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Ex/Em=325/393 nm. The kit provides a rapid, simple, sensitive and reliable test which can also be used as a high throughput assay of MMP-3 activity. The assay sensitivity is < 50 µU.Summary: - Detection method- Fluorescence (Ex/Em 325/393 nm) - Sample type- Cell and Tissue culture supernatants, urine, plasma and serum, as well as many other biological fluids, growth medium, food etc. - Species reactivity- Mammalian - Applications- The assay sensitivity is < 50 µU. Kit components: - MMP-3 Assay Buffer - MMP-3 Substrate - Mca Standard (1mM) - MMP-3 Positive Control Features and Benefits: - Simple procedure; takes ~ 60 minutes - Fast and convenient - Sensitive assays for measuring MMP-3 in various biological samples Shipping Conditions: Gel pack
Additional Information:
| MMP-3 Activity Assay Kit |
| MMP-3 assay kit, MMP, MMP-3, Detect MMP-3, MMP3 assay, MMP3 quantification, MMP-3 detection, MMP-3 assay, MMP-3 quantification, MMP3 detection, |
| Assay Kit |
| -20C |
| Research Use Only |
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