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GenWay/Dehydroepiandrosterone-Sulfate ELISA Kit/GWB-46B3CF/96 TESTS
2026-08-23
Description:
| Dehydroepiandrosterone-Sulfate |
| Fertility. |
| Serum and plasma. |
| 0.044 ug/mL. |
| DHEA-S Enzyme Immunoassay Kit provides materials for the Quantitative Determination of DHEA-S in serum and plasma. |
| The GenWay DHEA-S Enzyme Immunoassay Kit provides materials for the quantitative determination of DHEA-S in serum and plasma.This assay is intended for research use only.Dehydroepiandrosterone (5-Androstene-3β-0L-17-one, Androstenolone, Dehydroisoandrosterone, Transdehydroandrosterone, DHEA) is a steroid hormone present in blood mostly in its sulfate form (DHEA-S).DHEA-S is a more specific product of the adrenals and measurements of this steroid are widely used in clinical practice. The clinical importance of plasma assays of DHEA-S is associated with the diagnosis of adrenal hyperplasia and differential diagnosis of hirsutism (1). |
| The GenWay DHEA-S ELISA Kit is a solid phase enzyme-linked immunosorbent assay (ELISA), based on the principle of competitive binding. The microtiter wells are coated with a polyclonal antibody directed towards a unique antigenic site of the DHEA-S molecule.Endogenous DHEA-S of a patient sample competes with a DHEA-S horseradish peroxidase conjugate for binding to the coated antibody. After incubation the unbound conjugate is washed off.The amount of bound peroxidase conjugate is reverse proportional to the concentration of DHEA-S in the sample. After addition of the substrate solution, the intensity of colour developed is reverse proportional to the concentration of DHEA-S in the patient sample. |
| When stored at 2°C-8°C unopened reagents will retain reactivity until expiration date. Do not use reagents beyond this date.All opened reagents must be stored at 2°C-8°C. Microtiter wells must be stored at 2°C-8°C. Once the foilbag has been opened, care should be taken to close it tightly again. |
| Catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands. |
| 3-phosphoadenylyl sulfate + glycolithocholate = adenosine 3,5-bisphosphate + glycolithocholate 3-sulfate3-phosphoadenylyl sulfate + taurolithocholate = adenosine 3,5-bisphosphate + taurolithocholate sulfate. |
| Homodimer. |
| Cytoplasm. |
| Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney. |
| The N-terminus is blocked. |
| Estrogens present in maternal circulation is predominantly derived from fetal dehydroepiandosterone sulfate which is hydrolyzed and metabolized to estrogens in placenta. |
| Belongs to the sulfotransferase 1 family. |
Additional Information:
| Dehydroepiandrosterone-Sulfate ELISA Kit |
| Dehydroepiandrosterone-Sulfate ELISA Kit; EC 2.8.2.14; Hydroxysteroid Sulfotransferase; HST; Dehydroepiandrosterone sulfotransferase; DHEA-ST; ST2; ST2A3 HST; STDDehydroepiandrosterone-SulfateDHEA-S |
| NP_003158.2 |
| 33780 |
| Q06520 |
| Research Use Only |
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