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PTPRF FISH Probe
2025-06-25
| 货号： | FA0035 |
| Product Description： | Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. () |
| Supplied Product： | DAPI Counterstain (1500 ng/mL ) 250 uL |
| Storage Instruction： | Store at 4°C in the dark. |
| Origin： | Human |
| Source： | Genomic DNA |
| Notice： | We the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: or ) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections. |
| Regulation Status： | For research use only (RUO) |
| Gene Name： | PTPRF |
| Gene Alias： | FLJ43335,FLJ45062,FLJ45567,LAR |
| Gene Description： | protein tyrosine phosphatase, receptor type, F |
| Gene Summary： | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq |
| Other Designations： | LCA-homolog,OTTHUMP00000008684,leukocyte antigen-related (LAR) PTP receptor,leukocyte antigen-related tyrosine phosphatase,protein tyrosine phosphatase, receptor type, F polypeptide,receptor-linked protein-tyrosine phosphatase LAR |
| 规格： | 200 uL |
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