| Cat.No.147208 | 50 µg purified IgG, lyophilized. For reconstitution add 50µlH2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use. |
| Applications | WB:not recommended (see remarks) IP:not recommended (see remarks) ICC:1 : 500galleryIHC:not tested yetIHC-P/FFPE:not tested yet |
| Clone | RtmAb7a |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Native Protein corresponding to AA 1 to 768 from rat Gephyrin (UniProt Id: Q03555) |
| Epitop | Epitop: AA 264 to 276 from rat Gephyrin (UniProt Id: Q03555) |
| Reactivity | Reacts with: human (Q9NQX3), rat (Q03555), mouse (Q8BUV3), pig, goldfish, zebrafish.Other species not tested yet. |
| Specificity | Specific for the brain specific 93kDa splice variant. (K.O.verified) |
| Remarks | WB:Clone 3B11 (cat. no. 147 111) highly recommended. IP:Clone 3B11 (cat. no. 147 111) highly recommended.This antibody is a chimeric antibody based on the well known monoclonal mouse antibody mAb7a. The constant regions of the heavy and light chains have been replaced with rat specific sequences. The antibody can therefore be used with standard anti-rat secondary reagents. It also carries a Strep-tag at the C-terminus of the heavy chain.The antibody has been expressed in mammalian cells.The Twin-Strep-tag® contained in this product is licensed from IBA GmbH, Rudolf-Wissell-Str. 28, D-37079 Göttingen, Germany, and is provided for research use only. Information about licenses for commercial use of the Twin-Strep-tag® is available from the licenser. |
| Datasheet | 147_208.pdf |
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所以一个细菌或病毒可以有很多的抗原。
若已进入细胞内。则先由巨噬细胞吞噬降解。并形成抗原-MHC复合体传送到表面。被辅助性T淋巴细胞识别和效应T淋巴细胞识别后。效应T淋巴细胞被激活。分解靶细胞。然后再由效应B细胞分泌的抗体进一步消灭病毒。
还有不清楚的么?
荚膜(capsule)是某些细菌在生长繁殖过程中分泌的一层黏液性物质,包围在细胞壁外,通常这种黏液层厚度小于0.2μm,成分是多糖或多肽,只有在营养丰富时或在动物体内,细菌才产生这种半抗原性质的黏液性物质。它具有保护菌体免受巨噬细胞等的捕捉和吞噬,因而具有抗吞噬抗消化、侵袭力强、与致病性关系密切等特点。像肺炎球菌、炭疽杆菌等都有这类荚膜。有些细菌的荚膜层较薄,小于0.2μm,称为微荚。
像链球菌的M蛋白、伤寒杆菌的Vi抗原、大肠杆菌的K抗原等都属于这类微荚膜。
请赐教!

