定量PCR仪选择宝典 实验方法
RabbitAnti-AU5tag antibody
| 产品编号 | hz-2113R |
| 英文名称 | AU5tag |
| 中文名称 | AU5tag标签抗体 |
| 别 名 | AU5epitopetag;TDFYLKepitopetag;TDFYLKtag. |
| 产品类型 | 标签抗体 |
| 研究领域 | 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | fusionprotein,taggedT7tag |
| 产品应用 | ELISA=1:500-1000 ICC=1:100-500 （石蜡切片需做抗原修复） notyettestedinotherapplications.optimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| 性 状 | LyophilizedorLiquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLHconjugatedtoAU5tag: |
| 亚 型 | IgG |
| 纯化方法 | affinitypurifiedbyProteinA |
| 储 存 液 | 0.01MTBS(pH7.4)with1%BSA,0.03%Proclin300and50%Glycerol. |
| 保存条件 | Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C. |
| PubMed | PubMed |
| 产品介绍 | background:CoreproteinpackagesviralRNAtoformaviralnucleocapsid,andpromotesvirionbudding.ModulatesviraltranslationinitiationbyinteractingwithHCVIRESand40Sribosomalsubunit.Alsoregulatesmanyhostcellularfunctionssuchassignalingpathwaysandapoptosis.Preventstheestablishmentofcellularantiviralstatebyblockingtheinterferon-alpha/beta(IFN-alpha/beta)andIFN-gammasignalingpathwaysandbyinducinghumanSTAT1degradation.Playsanimportantroleinvirus-mediatedcelltransformationleadingtohepatocellularcarcinomas.Interactswith,andactivatesSTAT3leadingtocellulartransformation.Mayrepressthepromoterofp53,andsequesterCREB3andSP110isoform3/Sp110binthecytoplasm.AlsorepressescellcyclenegativeregulatingfactorCDKN1A,therebyinterruptinganimportantcheckpointofnormalcellcycleregulation.Targetstranscriptionfactorsinvolvedintheregulationofinflammatoryresponsesandintheimmuneresponse:suppressesNK-kappaBactivation,andactivatesAP-1.MediatesapoptoticpathwaysthroughtassociationwithTNF-typereceptorsTNFRSF1AandLTBR,althoughitseffectondeathreceptors-inducedapoptosisremainscontrovertial.EnhancesTRAILmediatedapoptosis,suggestingthatitmightplayaroleinmediatedapoptosis,suggestingthatitmightplayaroleinimmune-mediatedlivercellinjury.SecretedcoreproteinisabletobindC1QR1attheT-cellsurface,resultingindown-regulationofT-lymphocytesproliferation.MaytransactivatehumanMYC,RoussarcomavirusLTR,andSV40promoters.MaysuppressthehumanFOSandHIV-1LTRactivity.Mayalterlipidmetabolismbyinteractingwithhepatocellularproteinsinvolvedinlipidaccumulationandstorage.GeneID:AU5tagImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications |
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发布于 ： 2021-09-15
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