antiCCP, mAb (12G1)
ProductDetails | |
---|---|
Synonyms | CAT;Catalase;EC=1.11.1.6 |
ProductType | MonoclonalAntibody |
Properties | |
Clone | 11A1 |
Isotype | MouseIgG2aκ |
Immunogen/Antigen | RecombinanthumanproteinpurifiedfromE.coli. |
Application | WesternBlot(1:100~1,000) |
Crossreactivity | Human Mouse Rat |
PurityDetail | Ammoniumsulfateprecipitation. |
Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
Declaration | ManufacturedbyAbFrontier |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
Use/Stability | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
Catalaseisahomotetramericheme-containingenzymepresentwithinthematrixofallperoxisomes.Itcarriesoutadismutationreactioninwhichhydrogenperoxideisconvertedtowaterandoxygen.Humancatalasehasthelastfouraminoacids(-KANL)attheextremeC-terminusforperoxisometargeting.Themonomerofhumancatalaseis61.3kDainmolecularsize.Catalasehasbeenimplicatedasanimportantfactorininflammation,mutagenesis,preven-tionofapoptosis,andstimulationofawidespectrumoftumors.Lossofcatalaseleadstothehumangeneticdisease,acatalasemia,orTakahara’sdisease(1).Occursinalmostallaerobicallyrespiringorganismsandservestoprotectcellsfromthetoxiceffectsofhydrogenperoxide.PromotesgrowthofcellsincludingT-cells,β-cells,myeloidleukemiacells,melanomacells,mastocytomacellsandnormalandtransformedfibroblastcells.
ProductReferences
1)Tainer,J.A.etal.(2000)JMolBiol.296(1):295-309.(General)
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发布于 : 2021-08-03
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