antiCCP, mAb (12G1)
| ProductDetails | |
|---|---|
| Synonyms | CAT;Catalase;EC=1.11.1.6 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 11A1 |
| Isotype | MouseIgG2aκ |
| Immunogen/Antigen | RecombinanthumanproteinpurifiedfromE.coli. |
| Application | WesternBlot(1:100~1,000) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/Stability | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Catalaseisahomotetramericheme-containingenzymepresentwithinthematrixofallperoxisomes.Itcarriesoutadismutationreactioninwhichhydrogenperoxideisconvertedtowaterandoxygen.Humancatalasehasthelastfouraminoacids(-KANL)attheextremeC-terminusforperoxisometargeting.Themonomerofhumancatalaseis61.3kDainmolecularsize.Catalasehasbeenimplicatedasanimportantfactorininflammation,mutagenesis,preven-tionofapoptosis,andstimulationofawidespectrumoftumors.Lossofcatalaseleadstothehumangeneticdisease,acatalasemia,orTakahara’sdisease(1).Occursinalmostallaerobicallyrespiringorganismsandservestoprotectcellsfromthetoxiceffectsofhydrogenperoxide.PromotesgrowthofcellsincludingT-cells,β-cells,myeloidleukemiacells,melanomacells,mastocytomacellsandnormalandtransformedfibroblastcells.
ProductReferences
1)Tainer,J.A.etal.(2000)JMolBiol.296(1):295-309.(General)
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发布于 ： 2021-08-03
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