TheH57-597monoclonalantibodyreactswiththebetachainofthemouseTcellreceptor(TCR).TCRβbelongstotheimmunoglobulinsuperfamilyandisexpressedbythymocytesandTlymphocytes.TCRβcombineswithTCRαtoformTCRα/β.TCRα/βplaysacentralroleinantigenrecognition,signaltransduction,andTcellactivation.TheH57-597antibodyhasbeenshowntodepleteTCRα/βbearingTcellsfollowinginvivoadministration.
| Isotype | ArmenianHamsterIgG  | 
| RecomendedIsotypeControl(s) | InVivoMAbpolyclonalArmenianhamsterIgG | 
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer | 
| Immunogen | AffinitypurifiedTCRfrommouseDO-11.10cells  | 
| ReportedApplications | invivoTcelldepletion  | 
| Endotoxin | 
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| Purity | 
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| Formulation | 
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| Sterility | 0.2μMfiltered  | 
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility  | 
| Purification | ProteinG  | 
| Storage | Undilutedat4°Cinthedark  | 
                    