TheH57-597monoclonalantibodyreactswiththebetachainofthemouseTcellreceptor(TCR).TCRβbelongstotheimmunoglobulinsuperfamilyandisexpressedbythymocytesandTlymphocytes.TCRβcombineswithTCRαtoformTCRα/β.TCRα/βplaysacentralroleinantigenrecognition,signaltransduction,andTcellactivation.TheH57-597antibodyhasbeenshowntodepleteTCRα/βbearingTcellsfollowinginvivoadministration.
| Isotype | ArmenianHamsterIgG |
| RecomendedIsotypeControl(s) | InVivoMAbpolyclonalArmenianhamsterIgG |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer |
| Immunogen | AffinitypurifiedTCRfrommouseDO-11.10cells |
| ReportedApplications | invivoTcelldepletion |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Undilutedat4°Cinthedark |
