TheJ11dmonoclonalantibodyreactswithmouseCD24alsoknownasheatstableantigen(HSA),a35-50kDaglycosylatedmembraneprotein.CD24isexpressedbyerythrocytes,granulocytes,monocytes,andlymphocytes.ImmatureBcellsinbonemarrowandspleenofadultmiceexpresshighlevelsofCD24,whilematureperipheralBcellsexpressintermediatelevelsofCD24.TheexpressionofCD24hasbeenusedtoresolvestagesofBcelllymphopoiesisinmousebonemarrow.IthasbeenreportedthatP-selectin(CD62P)bindstoCD24.TheJ11dantibodyhasbeenshowntodepleteCD24+cellswhenadministeredinvivo.
| Isotype | RatIgM, κ  | 
| RecomendedIsotypeControl(s) | InVivoMAbpolyclonalratIgG | 
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer | 
| Immunogen | C3H/HeJmousethymocytes  | 
| ReportedApplications | invitroCD24+celldepletion  | 
| Endotoxin | 
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| Purity | 
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| Formulation | 
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| Sterility | 0.2μMfiltered  | 
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility  | 
| Purification | T-Gel  | 
| Storage | Undilutedat4°Cinthedark  | 
                    