TheJ11dmonoclonalantibodyreactswithmouseCD24alsoknownasheatstableantigen(HSA),a35-50kDaglycosylatedmembraneprotein.CD24isexpressedbyerythrocytes,granulocytes,monocytes,andlymphocytes.ImmatureBcellsinbonemarrowandspleenofadultmiceexpresshighlevelsofCD24,whilematureperipheralBcellsexpressintermediatelevelsofCD24.TheexpressionofCD24hasbeenusedtoresolvestagesofBcelllymphopoiesisinmousebonemarrow.IthasbeenreportedthatP-selectin(CD62P)bindstoCD24.TheJ11dantibodyhasbeenshowntodepleteCD24+cellswhenadministeredinvivo.
| Isotype | RatIgM, κ |
| RecomendedIsotypeControl(s) | InVivoMAbpolyclonalratIgG |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer |
| Immunogen | C3H/HeJmousethymocytes |
| ReportedApplications | invitroCD24+celldepletion |
| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | T-Gel |
| Storage | Undilutedat4°Cinthedark |
